abstract：:The quantitative autoradiographic 2-[14C]deoxyglucose method was employed to map the metabolic activity of the superior cervical ganglion and the entire brain during unilateral electrical stimulation of the cervical sympathetic trunk in the urethane-anesthetized rat. Stimulation of the cervical sympathetic trunk incre...

journal_title：Journal of pineal research

authors： Ito M,Kadekaro M,Sokoloff L

更新日期：1988-01-01 00:00:00

abstract：:The distribution of 14C-Melatonin (14C-MT) after systemic injection was studied in the plasma, cerebrospinal fluid (CSF), and brain of rats. Chromatographic analysis (thin-layer chromatography and high-performance liquid chromatography) indicated that the radioactivity from biological samples taken at various times fo...

journal_title：Journal of pineal research

authors： Vitte PA,Harthe C,Lestage P,Claustrat B,Bobillier P

更新日期：1988-01-01 00:00:00

abstract：:Female Syrian hamsters were kept in a light (14:10 h light:dark cycle, lights on 0600 h)- and temperature (22 or 30 degrees C)-controlled room; some groups were treated with an afternoon s.c. injection of melatonin (6.25, 12.5, or 25 micrograms/day) for 11 or 14 weeks. The melatonin-induced suppression of the reproduc...

journal_title：Journal of pineal research

authors： Reiter RJ,Li K,Gonzalez-Brito A,Tannenbaum MG,Vaughan MK,Vaughan GM,Villanua MA

更新日期：1988-01-01 00:00:00

abstract：:The milk-ejecting response of lactating mouse mammary gland tissue to ovine pineal extracts indicated the presence of a neurohormone-like bioactivity in this tissue. After successive fractionation on gel permeation chromatography and reversed-phase liquid chromatography (HPLC) in conjunction with radioimmunoassays (RI...

journal_title：Journal of pineal research

authors： Noteborn HP,Ebels I,Reinharz AC,Pévet P,Benson B,Salemink CA

更新日期：1988-01-01 00:00:00

abstract：:The effect of various cations on activity of hydroxyindole-O-methyltransferase (HIOMT) and N-acetyltransferase (NAT) from pineal gland was studied. Copper inhibited both enzymes while calcium and magnesium inhibited HIOMT; the mechanisms of these inhibitions are unknown at this stage. Calcium, magnesium, potassium, an...

journal_title：Journal of pineal research

authors： Morton DJ

更新日期：1987-01-01 00:00:00

abstract：:The binding characteristics of the tritiated pineal hormone, [3H] melatonin, were studied in brain tissues using in vitro binding techniques. In synaptosomal membranes prepared from rat hippocampus and subjected to preincubation at 37 degrees C and multiple washings, high-affinity binding of [3H] melatonin significant...

journal_title：Journal of pineal research

authors： Niles LP

更新日期：1987-01-01 00:00:00

abstract：:The activity of N-acetyltransferase (NAT) and the content of melatonin (MEL) in the rat pineal have been shown to be sensitive to several types of stressors. This study was designed to assess the role of the adrenals in mediating the effect of one such stressor, insulin-induced hypoglycemia, on pineal synthetic activi...

journal_title：Journal of pineal research

authors： Tannenbaum MG,Reiter RJ,Vaughan MK,Troiani ME,Gonzalez-Brito A

更新日期：1987-01-01 00:00:00

abstract：:The present study analyzes the participation of pineal stalk and superior cervical ganglia (SCG) in the conduction of photic evoked potentials (PEP) to the pineal body (PB) in unanesthetized freely moving rats implanted with semimicroelectrodes. The PEPs were recorded in PB, lateral hypothalamus (LH), and habenular co...

journal_title：Journal of pineal research

authors： Barajas-López C,Barrientos-Martinez MA,Reyes-Vázquez C

更新日期：1987-01-01 00:00:00

abstract：:The effect of anticonvulsant drugs on daytime and nighttime N-acetyltransferase (NAT) and hydroxyindole-O-methyltransferase (HIOMT) levels was investigated. Some of the drugs caused a significant reduction in daytime NAT and HIOMT levels, possibly owing to beta-receptor blockade although other mechanisms cannot be exc...

journal_title：Journal of pineal research

authors： Morton DJ

更新日期：1986-01-01 00:00:00

abstract：:Experiments were designed to test the hypothesis that the pineal gland mediates the effects of changing day length and thereby synchronizes implantation within the population of spotted skunks. Intact, sham-superior cervical ganglionectomized (SCGx), SCGx, and SCGx/bilateral orbitally enucleated (B1) pregnant skunks w...

journal_title：Journal of pineal research

authors： May R,Mead RA

更新日期：1986-01-01 00:00:00

abstract：:Melatonin injected in a single intraperitoneal dose of 100 micrograms/100 g b.w. to euhydrated rats resulted in a decrease of neurohypophysial oxytocin content but the hypothalamic oxytocin storage as well as the hypothalamo-neurohypophysial storage of vasopressin were not changed. Following 8 d of once-daily melatoni...

journal_title：Journal of pineal research

authors： Juszczak M,Guzek JW,Lewy A

更新日期：1986-01-01 00:00:00

abstract：:Rat pineal hydroxyindole-O-methyltransferase (HIOMT; EC 2.1.1.4) was purified by affinity chromatography using an S-adenosyl-L-homocysteine agarose column. This single-step procedure, which is rapid, simple, and applicable to small quantities of tissue, gave a large enrichment of a protein (Mr approximately 38,000) id...

journal_title：Journal of pineal research

authors： Sugden D,Voisin P,Klein DC

更新日期：1986-01-01 00:00:00

abstract：:Djungarian hamsters kept in long photoperiod (16:8 L:D) were injected daily at 0800, 1200, or 1600 with 25 micrograms of melatonin. During 90 days of treatment, body weight and fur coloration were checked at weekly intervals, and at the end of the treatment the reproductive status of the hamsters and their thermoregul...

journal_title：Journal of pineal research

authors： Holtorf AP,Heldmaier G,Thiele G,Steinlechner S

更新日期：1985-01-01 00:00:00

abstract：:Four-week-old male hamsters, born and raised in total darkness or in LD 14:10 (hr) were exposed to several low levels of illumination for 14 weeks. Analyses showed that testicular weights were significantly affected by both photic history and illuminance levels. Animals born in the dark possessed larger testes than th...

journal_title：Journal of pineal research

authors： Hoffman RA,Johnson LB

更新日期：1985-01-01 00:00:00

abstract：:The effects of housing condition and type of stimulation on serum melatonin and N-acetylserotonin (NAS) were investigated. Male rats were housed under a 12/12-hour light-dark cycle, with ad libitum food and water, either individually or in groups of four. At the start of the light phase, separate groups were sacrifice...

journal_title：Journal of pineal research

authors： Seggie J,Campbell L,Brown GM,Grota LJ

更新日期：1985-01-01 00:00:00

abstract：:The serum levels of the pineal hormone melatonin were determined by radioimmunoassay (RIA) in 4-h intervals throughout a 24-h period in elderly men with different types of prostate tumors: benign prostatic hyperplasia (BPH, n = 13), incidental carcinoma (PCi, n = 5), and nonmetastasizing carcinoma (PC, n = 9), as well...

journal_title：Journal of pineal research

authors： Bartsch C,Bartsch H,Flüchter SH,Attanasio A,Gupta D

更新日期：1985-01-01 00:00:00

abstract：:In three separate experiments, the effect of acute exposure to either artificial or natural light during darkness of pineal N-acetyltransferase (NAT) activity and melatonin content was studied in the cotton rat (Sigmodon hispidus). The exposure of animals to an artificial-light irradiance of 160,000 microW/cm2 during ...

journal_title：Journal of pineal research

authors： Nürnberger F,Joshi BN,Heinzeller T,Milin J,Reiter RJ

更新日期：1985-01-01 00:00:00

abstract：:The purpose of this study was to define the peripubertal changes in prolactin (PRL) synthesis in blind-anosmic female rats. To do this prepubertal female rats were either rendered blind-anosmic (BA) or blind-anosmic-pinealectomized (BAP) or left intact (INT). Half the animals were killed after 1 wk (before puberty) wh...

journal_title：Journal of pineal research

authors： Leadem CA,Blask DE

更新日期：1984-01-01 00:00:00

abstract：:The purpose of the present studies using artificial light was to determine how the timing and duration of exposure influence the light-induced suppression of pineal melatonin levels in hamsters. An 8-min exposure to 0.186 microW/cm2 of cool white fluorescent light caused a continued depression of pineal melatonin even...

journal_title：Journal of pineal research

authors： Brainard GC,Richardson BA,Hurlbut EC,Steinlechner S,Matthews SA,Reiter RJ

更新日期：1984-01-01 00:00:00

abstract：:Adult female golden hamsters were used to study the effect of short photoperiod on the endogenous opioid system and the effect of pinealectomy on the serum beta-endorphin-like immunoreactivity (beta-end LI) levels. Hamsters were housed under either long photoperiod (14L:10D) or short photoperiod (2L:22D) and the regul...

journal_title：Journal of pineal research

authors： Kumar MS,Besch EL,Millard WJ,Sharp DC,Leadem CA

更新日期：1984-01-01 00:00:00